A vial of the Oxford-AstraZeneca COVID-19 vaccine is seen with injection supplies at a clinic in Winnipeg on March 19, 2021. THE CANADIAN PRESS/John Woods

A vial of the Oxford-AstraZeneca COVID-19 vaccine is seen with injection supplies at a clinic in Winnipeg on March 19, 2021. THE CANADIAN PRESS/John Woods

Health Canada says AstraZeneca vaccine safe, effective but will add warning on clots

Canada has thus far received about 500,000 doses of the Oxford-AstraZeneca vaccine

Health Canada is devising a warning about a rare possible side-effect of blood clots from the Oxford-AstraZeneca vaccine but is still certain the inoculation is safe and effective against COVID-19.

The department’s chief medical adviser Dr. Supriya Sharma said Tuesday the plan for a warning comes on the heels of a similar move in Europe last week but doesn’t change Health Canada’s analysis that the vaccine’s benefits outweigh its risks.

“We were observers at that European Medicines Agency subcommittee meeting, we’ve looked at the data as well,” she said. “And so we’re in the process of making similar changes to the information for Canadians.”

The European Medicines Agency last week amended its authorization of the vaccine to say there is no overall increase in the risk of blood clots after getting the vaccine but added a warning that a small number of patients had developed rare blood clots in the brain after getting it.

At the time the EMA couldn’t say if the clots were related to the vaccine. German and Norwegian scientists have since said in a very small number of patients the vaccine is causing an extreme immune response that is leading to the clots. It is a treatable condition, they said.

The EMA reported 18 cases of cerebral venous sinus thrombosis, out of about 20 million people who received the Oxford-AstraZeneca vaccine in Europe, the United Kingdom, and India, and seven cases of another type of clotting disorder related to very low platelet counts.

Sharma said the vaccine is still hugely beneficial, including protecting against severe illness and death from the novel coronavirus’s variants of concern, but Health Canada is looking to adjust the label on the vaccine to note the reports of the rare types of clots and potential symptoms that could occur. Those include, she said, persistent and intense headaches that last for several days, shortness of breath and pain in the legs.

Sharma said there is no doubt all of the reports about this vaccine are a concern because they feed fears about its safety. She said Health Canada will continue to provide accurate and current information so Canadians can trust the vaccine is safe to get.

“We’ve said this many times before, that even the most effective vaccine only works if people trust it and agree to receive it,” she said. “It’s like any other reputation — once there’s some doubt that creeps into that reputation, it’s that much more difficult to gain that back.”

Canada has thus far received about 500,000 doses of the Oxford-AstraZeneca vaccine and expects to get 1.5 million more as soon as this week from the United States.

Even without those doses Canada’s deliveries of more than two million doses of other COVID-19 vaccines from Pfizer-BioNTech and Moderna are the most in a week yet. Though the first of two shipments expected from Moderna has been delayed a day, arriving Wednesday instead of Tuesday.

More than 3.5 million people in Canada have received at least one dose now.

Chief public health officer Dr. Theresa Tam said she knows everyone is tired of the “tricks and turns of this virus” and said there are many reasons to be hopeful, including the faster pace of vaccinations.

Still she warned, variants of concern continue to rise and the number of new COVID-19 cases rose 15 per cent over the last week. In turn, the numbers of people in hospital overall, and those needing intensive care, are creeping upwards.

In the last week an average of 2,100 people were in hospital in Canada being treated for COVID-19 on any given day, including 580 in critical care, compared to 2,040 in hospital and 550 in ICUs a week ago.

Since vaccinations began, COVID-19 infection rates in people over 80 have slowed, said Tam, but younger people, particularly under the age of 40, are seeing higher rates.

Dr. Deena Hinshaw, the chief medical officer of health in Alberta, said 88 per cent of the 48 patients in intensive care in that province are under age 65. Hinshaw said people need to continue to make good decisions to keep the spread of the virus down.

“Now is not the time to abandon the practices that have protected our communities and health care system over the past year,” said Hinshaw on Twitter. “Once we hit a growth phase of this virus, our #s will not stand still.”

READ MORE: Canadian doctors say getting COVID-19 poses greater risk of blood clots than the vaccine

Mia Rabson, The Canadian Press


Like us on Facebook and follow us on Twitter.

Want to support local journalism during the pandemic? Make a donation here.

Coronavirusvaccines

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

B.C's COVID-19 dashboard shows the peaks and valleys of cases prior to the record daily report of 132 on April 9, 2021. (Dashboard image)
Interior Health has record day of COVID-19 cases

132 cases reported Friday, April 9, more deaths in Vernon hospital outbreak

(Black Press files)
Chief Civilian Director Ronald J. McDonald, QC reviewed the evidence and determined reasonable grounds exist to believe in officer may have committed offenses. (Black Press files)
Crown considering charges against Williams Lake Mountie after high-speed pursuit: police watchdog

IIO says the man, who was arrested, sustained serious but not life-threatening injuries from the incident

Sarah Smith is a bereavement worker with 100 Mile Hospice. (Kelly Sinoski - 100 Mile Free Press).
‘Grief never goes away’: Hospice seeks to add programs

Growing demand for bereavement services in the South Cariboo region.

Abstract Aspens by Monika Paterson.
Photography exhibits all Shades of Nature

Parkside Gallery features local art

B.C. Health Minister Adrian Dix and Premier John Horgan describe vaccine rollout at the legislature, March 29, 2021. (B.C. government)
1,262 more COVID-19 infections in B.C. Friday, 9,574 active cases

Province’s mass vaccination reaches one million people

A large illuminated heart was installed on the roof of the Vernon Jubilee Hospital May 1, 2020. (VJH Foundation photo)
Three deaths linked to COVID-19 outbreak in Vernon hospital

Interior Health reports two additional deaths at VJH

Robinson Russ, 37, was fatally stabbed on April 4, according to a statement from police. THE CANADIAN PRESS/Darryl Dyck
Vancouver police name victim following city’s fourth homicide of 2021

Robinson Russ, 37, was fatally stabbed Sunday in the Downtown Eastside

A man wears a face mask past the emergency department of the Vancouver General Hospital. (THE CANADIAN PRESS/Jonathan Hayward)
Calls for stricter action in B.C. as COVID-19 variants projected to climb

Jens von Bergmann says the province has taken a ‘wait and see’ approach when early action is needed

Vancouver’s park board general manager issued a new order Friday restricting tents and other temporary structures from being set up in Strathcona Park after April 30, 2021. THE CANADIAN PRESS/Jonathan Hayward
Vancouver park board issues order to restrict tents in Strathcona Park

The order issued Friday restricted tents and other temporary structures from being set up after April 30

Vancouver Canucks general manager Jim Benning says the players who’ve tested positive for COVID-19 are recovering and the team still intends to play a 56-game season. THE CANADIAN PRESS/Darryl Dyck
Canucks players ‘mostly on the other side’ of COVID outbreak: general manager

The athletes have had a “whole range” of COVID-19 symptoms, said team physician Dr. Jim Bovard, but no one has needed to be hospitalized

Police are investigating after a man was shot Thursday, April 8 while sitting in a car in Vancouver. (Black Press files)
Man shot in Vancouver while sitting in a parked car: police

The victim is currently in critical condition. Police say no arrests have been made.

Teachers from SD42 and other districts in the Lower Mainland flocked to Surrey on Tuesday in the hopes of getting a COVID-19 vaccine. (Sheelagh Brothers/Twitter)
Don’t line up for vaccines unless asked to come, Dr. Bonnie Henry warns

Social media post shows teachers lining up outside of Surrey clinic for leftover doses

Most Read